Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

Zhang X, Choi PS, Francis JM, Imielinski M, Watanabe H, Cherniack AD, Meyerson M.

Nature Genetics 2016 Feb;48(2):176–82.

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.

Campbell JD, Alexandrov A, Kim J, Wala J, Berger AH, Pedamallu CS, Shukla SA, Guo G, Brooks AN, Murray BA, Imielinski M, Hu X, Ling S, Akbani R, Rosenberg M, Cibulskis C, Ramachandran A, Collisson EA, Kwiatkowski DJ, Lawrence MS, Weinstein JN, Verhaak RGW, Wu CJ, Hammerman PS, Cherniack AD, Getz G, TCGA Network, Artyomov MN, Schreiber R, Govindan R, Meyerson M.

Nature Genetics 2016 Jun;48(6):607–16.

High-throughput Phenotyping of Lung Cancer Somatic Mutations.

High-throughput Phenotyping of Lung Cancer Somatic Mutations.

Berger AH, Brooks AN, Wu X, Shrestha Y, Chouinard C, Piccioni F, Bagul M, Kamburov A, Imielinski M, Hogstrom L, Zhu C, Yang X, Pantel S, Sakai R, Watson J, Kaplan N, Campbell JD, Singh S, Root DE, Narayan R, Natoli T, Lahr DL, Tirosh I, Tamayo P, Getz G, Wong B, Doench J, Subramanian A, Golub TR, Meyerson M, Boehm JS.

Cancer Cell 2016 Aug 8;30(2):214–28.

Comprehensive molecular profiling of lung adenocarcinoma.

Comprehensive molecular profiling of lung adenocarcinoma.

TCGA Network.

Nature 2014 Jul 31;511(7511):543–50. 

Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma.

Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma.

Imielinski M, Greulich H, Kaplan B, Araujo L, Amann J, Horn L, Schiller J, Villalona-Calero MA, Meyerson M, Carbone DP.

Journal of Clinical Investigation 2014 Apr;124(4):1582–6. PMCID: PMC3973082

Oncogenic RIT1 mutations in lung adenocarcinoma.

Oncogenic RIT1 mutations in lung adenocarcinoma.

Berger AH, Imielinski M, Duke F, Wala J, Kaplan N, Shi G-X, Andres DA, Meyerson M.

Oncogene 2014 Aug 28;33(35):4418–23. PMCID: PMC4150988

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.

Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, Choi K, de Waal L, Sharifnia T, Brooks A, Greulich H, Banerji S, Zander T, Seidel D, Leenders F, Ansén S, Ludwig C, Engel-Riedel W, Stoelben E, Wolf J, Goparju C, Thompson K, Winckler W, Kwiatkowski D, Johnson BE, Jänne PA, Miller VA, Pao W, Travis WD, Pass HI, Gabriel SB, Lander ES, Thomas RK, Garraway LA, Getz G, Meyerson M.

Cell 2012 Sep 14;150(6):1107–20.

A landscape of driver mutations in melanoma.

A landscape of driver mutations in melanoma.

Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat J-P, Nickerson E, Auclair D, Li L, Place C, DiCara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DSB, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L.

Cell 2012 Jul 20;150(2):251–63.

Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse.

Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse.

Imielinski M, Cha S, Rejtar T, Richardson EA, Karger BL, Sgroi DC.

Molecular Cellular Proteomics 2012 Jun;11(6):M111.014910. PMCID: PMC3433899

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D, Western Regional Alliance for Pediatric IBD, Silber G, Wrobel I, Quiros A, International IBD Genetics Consortium, Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, et al.

Nature Genetics 2009 Dec;41(12):1335–40. 

Variants of DENND1B associated with asthma in children.

Variants of DENND1B associated with asthma in children.

Sleiman PMA, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SAG, Wang K, Rafaels NM, Michel S, Bønnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JS, Orange JM, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, Mutius von E, Cookson WOC, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SFA, Bisgaard H, Hakonarson H.

New England Journal of Medicine 2010 Jan 7;362(1):36–44. 

In situ proteomic analysis of human breast cancer epithelial cells using laser capture microdissection

In situ proteomic analysis of human breast cancer epithelial cells using laser capture microdissection

Cha S, Imielinski MB, Rejtar T, Richardson EA, Thakur D, Sgroi DC, Karger BL.

Mol. Cell Proteomics. 2010 Nov;9(11):2529–44. PMCID: PMC2984225

Deep epistasis in human metabolism.

Deep epistasis in human metabolism.

Imielinski M, Belta C.

Chaos 2010 Jun;20(2):026104.

Exploiting the pathway structure of metabolism to reveal high-order epistasis.

Exploiting the pathway structure of metabolism to reveal high-order epistasis.

Imielinski M, Belta C.

BMC Systems Biology 2008 Apr 30;2(1):40.

Systematic analysis of conservation relations in Escherichia coli genome-scale metabolic network reveals novel growth media.

Systematic analysis of conservation relations in Escherichia coli genome-scale metabolic network reveals novel growth media.

Imielinski M, Belta C, Rubin H, Halász A.

Biophysical Journal 2006 Apr 15;90(8):2659–72. 

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.
High-throughput Phenotyping of Lung Cancer Somatic Mutations.
Comprehensive molecular profiling of lung adenocarcinoma.
Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma.
Oncogenic RIT1 mutations in lung adenocarcinoma.
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.
A landscape of driver mutations in melanoma.
Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse.
Common variants at five new loci associated with early-onset inflammatory bowel disease.
Variants of DENND1B associated with asthma in children.
In situ proteomic analysis of human breast cancer epithelial cells using laser capture microdissection
Deep epistasis in human metabolism.
Exploiting the pathway structure of metabolism to reveal high-order epistasis.
Systematic analysis of conservation relations in Escherichia coli genome-scale metabolic network reveals novel growth media.